BDBM10262 Isoquinoline-1,3,4-trione 6i::methyl 3-nitro-5-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)carbamoyl]benzoate

SMILES COC(=O)c1cc(cc(c1)N(=O)=O)C(=O)Nc1cccc2C(=O)NC(=O)C(=O)c12

InChI Key InChIKey=FUZZVEDEBANLPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10262   

TargetCaspase-3(Homo sapiens (Human))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10262(Isoquinoline-1,3,4-trione 6i | methyl 3-nitro-5-[(...)
Affinity DataIC50:  104nMAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed