BDBM194973 US9206198, 29
SMILES CC1CC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C(=O)N1C1=C(C)C(=O)OC1
InChI Key InChIKey=GZQBZFYKKVFELZ-YNNZGITBSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 194973
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 70nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384
wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in
Poly-D...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human ERG expressed in HEK-293 cells by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 18nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair