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Found 2 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM194973'
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM194973(US9206198, 29)
Affinity DataIC50:  18nMAssay Description:Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM194973(US9206198, 29)
Affinity DataIC50:  70nMT: 2°CAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent