BDBM28492 (3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyridin-3-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15d

SMILES Fc1cccc(COc2ccc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)cn2)c1

InChI Key InChIKey=NWRYHCNPTDKBAI-FYYLOGMGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28492   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Gsk

LigandPNGBDBM28492((3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyrid...)
Affinity DataIC50:  450nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM28492((3R,5S)-5-{2-[4-({6-[(3-fluorophenyl)methoxy]pyrid...)
Affinity DataIC50:  2.60E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed