BDBM50300744 3-cyano-4-(4-fluorophenyl)-1,2,5-oxadiazole 2-oxide::CHEMBL576118

SMILES [O-][n+]1onc(c1C#N)-c1ccc(F)cc1

InChI Key InChIKey=GXSQTUSGGZNZJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300744   

TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300744(3-cyano-4-(4-fluorophenyl)-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300744(3-cyano-4-(4-fluorophenyl)-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300744(3-cyano-4-(4-fluorophenyl)-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed