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Found 59 Enz. Inhib. hit(s) with Target = 'Thioredoxin glutathione reductase'
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50049873(CHEMBL3322287)
Affinity DataIC50:  10nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM35361((5-oxidanidyl-4-thiophen-2-ylcarbonyl-1,2,5-oxadia...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM47478(2-(4-chlorophenyl)sulfonyl-6-methoxy-3-nitro-pyrid...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300734(4-thienoyl-3-cyanofuroxan | CHEMBL576265)
Affinity DataIC50:  63nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50049868(CHEMBL3322292)
Affinity DataIC50:  83nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50532918(CHEMBL1325877)
Affinity DataIC50:  100nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50532918(CHEMBL1325877)
Affinity DataIC50:  100nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300756(3-formyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM57768(7-[(4-methoxyphenyl)-[(4-methyl-2-pyridinyl)amino]...)
Affinity DataIC50:  130nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50567349(CHEMBL4846043)
Affinity DataIC50:  140nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50049874(CHEMBL3322286)
Affinity DataIC50:  148nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM54510(5-chloranyl-N-[4-[ethyl(phenyl)sulfamoyl]phenyl]-2...)
Affinity DataIC50:  210nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50049872(CHEMBL3322288)
Affinity DataIC50:  316nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50567347(CHEMBL4852477)
Affinity DataIC50:  330nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300760(4,4'-(thiophene-2,4-diyl)bis(3-cyano-1,2,5-oxadiaz...)
Affinity DataIC50:  350nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50049867(CHEMBL3322293)
Affinity DataIC50:  350nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300761(4,4'-(thiophene-2,5-diyl)bis(3-cyano-1,2,5-oxadiaz...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300762(4,4'-(5-fluoro-1,3-phenylene)bis(3-cyano-1,2,5-oxa...)
Affinity DataIC50:  480nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300755(3-carboxy-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEM...)
Affinity DataIC50:  630nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300763(4,4'-(1,4-phenylene)bis(3-cyano-1,2,5-oxadiazole 2...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50396169(CHEMBL1337170)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300753(3-cyano-4-(3-nitrophenyl)-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300752(3-cyano-4-(3-(trifluoromethyl)phenyl)-1,2,5-oxadia...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300736(3-cyano-4-(furan-2-yl)-1,2,5-oxadiazole 2-oxide | ...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300750(4-(3-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300751(4-(3-bromo-4-fluorophenyl)-3-cyano-1,2,5-oxadiazol...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50567348(CHEMBL4858362)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 30 mins by DTNB assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50567346(CHEMBL4871407)
Affinity DataIC50:  3.15E+3nMAssay Description:Inhibition of Schistosoma mansoni thioredoxin glutathione reductase incubated for 50 mins by thio-glo reagent based fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300749(4-(3-chlorophenyl)-3-cyano-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300748(4-(4-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300759(4,4'-(1,3-phenylene)bis(3-cyano-1,2,5-oxadiazole 2...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300735(3-cyano-4-(thiophen-2-yl)-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300747(4-(4-chlorophenyl)-3-cyano-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50038412(2-Oxy-4-phenyl-furazan-3-carbonitrile | 3-cyano-4-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50038412(2-Oxy-4-phenyl-furazan-3-carbonitrile | 3-cyano-4-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM47913(MLS001030320 | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-...)
Affinity DataIC50:  7.08E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM47913(MLS001030320 | N-(4-nitro-1,2,5-oxadiazol-3-yl)-2-...)
Affinity DataIC50:  7.08E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300745(3-cyano-4-(3-hydroxyphenyl)-1,2,5-oxadiazole 2-oxi...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300746(3-cyano-4-(4-(trifluoromethyl)phenyl)-1,2,5-oxadia...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300743(3-cyano-4-(2-methoxyphenyl)-1,2,5-oxadiazole 2-oxi...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300744(3-cyano-4-(4-fluorophenyl)-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50049864(CHEMBL3322356)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of Schistosoma mansoni recombinant thioredoxin glutathione reductase assessed as 5-thio-2nitrobezoic acid formation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300742(3-cyano-4-(3,4,5-trimethoxyphenyl)-1,2,5-oxadiazol...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300741(3-cyano-4-(3-methoxyphenyl)-1,2,5-oxadiazole 2-oxi...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300740(3-cyano-4-(4-methoxyphenyl)-1,2,5-oxadiazole 2-oxi...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300739(3-cyano-4-p-tolyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300757(3-(hydroxymethyl)-4-phenyl-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50532917(CHEMBL1455957)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50300738(4-(biphenyl-4-yl)-3-cyano-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
Universit£

Curated by ChEMBL
LigandPNGBDBM50532917(CHEMBL1455957)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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