BDBM50300753 3-cyano-4-(3-nitrophenyl)-1,2,5-oxadiazole 2-oxide::CHEMBL570346

SMILES [O-][N+](=O)c1cccc(c1)-c1no[n+]([O-])c1C#N

InChI Key InChIKey=IWEBKPZVXTZZBD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300753   

TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300753(3-cyano-4-(3-nitrophenyl)-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300753(3-cyano-4-(3-nitrophenyl)-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300753(3-cyano-4-(3-nitrophenyl)-1,2,5-oxadiazole 2-oxide...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed