BDBM50300757 3-(hydroxymethyl)-4-phenyl-1,2,5-oxadiazole 2-oxide::CHEMBL567641

SMILES OCc1c(no[n+]1[O-])-c1ccccc1

InChI Key InChIKey=HSQJNPRERPSLPB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300757   

TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300757(3-(hydroxymethyl)-4-phenyl-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300757(3-(hydroxymethyl)-4-phenyl-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300757(3-(hydroxymethyl)-4-phenyl-1,2,5-oxadiazole 2-oxid...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed