BDBM100351 US10533001, Example Table 9a.4::US11414410, Table 9a.4::US8501944, 373::US8501944, 376::US9868729, Example 254

SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1

InChI Key InChIKey=UNRTWZKXADNVLM-GFCCVEGCSA-N

Data  2 IC50  20 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100351   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM100351(US10533001, Example Table 9a.4 | US11414410, Table...)
Affinity DataKd:  4.10nMAssay Description:The kinase reaction is performed in a black U-bottom 96-well microtitre plate. The final reaction volume is 50 μL and contains a final concentra...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Alexion Pharmaceuticals

US Patent
LigandPNGBDBM100351(US10533001, Example Table 9a.4 | US11414410, Table...)
Affinity DataKd:  14nMAssay Description:The kinase reaction is performed in a black U-bottom 96-well microtitre plate. The final reaction volume is 50 μL and contains a final concentra...More data for this Ligand-Target Pair
In DepthDetails US Patent