BDBM102970 US8541427, 41
SMILES COc1nc(nc(c1F)C(F)(F)F)N1C[C@H]2C(=O)N(C)C(N)=N[C@]2(C1)c1ccc(F)cc1F
InChI Key InChIKey=GGBFCIDHKFDBIK-XTZNXHDOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 102970
Affinity DataKi: 32nM ΔG°: -10.4kcal/mole IC50: 67nMT: 2°CAssay Description:A homogeneous time-resolved FRET assay was used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. The assay monit...More data for this Ligand-Target Pair