BDBM103449 US8552037, 97

SMILES CC(=O)NCCC1CCc2ccc3nc(C)sc3c12

InChI Key InChIKey=JDFVYDLICOGWLH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103449   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM103449(US8552037, 97)
Affinity DataKi:  0.0370nMAssay Description:Displacement of 2-[125l]-lodomelatonin from human MT1 expressed in CHO cell membrane incubated for 150 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM103449(US8552037, 97)
Affinity DataKi:  0.0860nMAssay Description:Displacement of 2-[125l]-lodomelatonin from human MT2 expressed in CHO cell membrane incubated for 150 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM103449(US8552037, 97)
Affinity DataIC50:  0.150nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM103449(US8552037, 97)
Affinity DataIC50:  0.280nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent