BDBM103910 JNK3 inhibitor 7::US8562945, 243

SMILES CN1C=C[N]2=C1C[N]1(CCc3ccc(SOON)cc3)CC3=[N](C=CN3C)[Re+]21

InChI Key InChIKey=JDWVJCDXGFYOOF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103910   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50:  564nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50:  155nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50:  127nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103910(JNK3 inhibitor 7 | US8562945, 243)
Affinity DataIC50:  652nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In DepthDetails US Patent