BDBM107099 US8592371, 1::US9278976, (3S,5R)-2-(2,5-difluorophenyl)-5-{2-methanesulfonyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}oxan-3-amine

SMILES CS(=O)(=O)n1cc2CN(Cc2n1)[C@H]1COC([C@@H](N)C1)c1cc(F)ccc1F

InChI Key InChIKey=MKMPWKUAHLTIBJ-AIMZMQLPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107099   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM107099(US8592371, 1 | US9278976, (3S,5R)-2-(2,5-difluorop...)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM107099(US8592371, 1 | US9278976, (3S,5R)-2-(2,5-difluorop...)
Affinity DataIC50:  2.5nMAssay Description:Enzyme assay using dipeptidyl peptidase-IV.More data for this Ligand-Target Pair
In DepthDetails US Patent