BDBM107728 US8933095, 12

SMILES Cc1c2C[C@H](N)C(=O)N(O)c2nn1Cc1ccccc1

InChI Key InChIKey=YCKBTRWHEXOAKG-LBPRGKRZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107728   

TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM107728(US8933095, 12)
Affinity DataIC50:  81.6nMT: 2°CAssay Description:Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM107728(US8933095, 12)
Affinity DataIC50:  81.6nMAssay Description:Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...More data for this Ligand-Target Pair
In DepthDetails US Patent