BDBM10866 4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide::CHEMBL418::aromatic/heteroaromatic sulfonamide 11

SMILES Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=KRVABEGPNKGLOT-UHFFFAOYSA-N

Data  102 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10866   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM10866(4-amino-6-(trifluoromethyl)benzene-1,3-disulfonami...)
Affinity DataIC50:  340nMAssay Description:Inhibitory concentration against human cystolic isozyme II of Carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10866(4-amino-6-(trifluoromethyl)benzene-1,3-disulfonami...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibitory concentration against human cystolic isozyme V of Carbonic anhydraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed