BDBM10908 3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::3-Dimethylamino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyridin-2(1H)-one::4-benzyl pyridinone derivative 27

SMILES CCc1c(C)[nH]c(=O)c(N(C)C)c1Cc1cc(C)cc(C)c1

InChI Key InChIKey=FHQCHOTUQBIXHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10908   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM10908(3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5...)
Affinity DataIC50:  8nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10908(3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5...)
Affinity DataIC50:  20nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed