BDBM111190 US10112950, Example 42::US10556908, Example 42::US9695180, 42

SMILES CN(C)Cc1cn2c(-c3ccc(C)cc3)c(nc(OC[C@@H]3CCNC3)c2n1)-c1ccc(cc1)C#N

InChI Key InChIKey=UUNQTJAQDFYPHC-OAQYLSRUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 111190   

TargetLysine-specific histone demethylase 1A [151-852](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM111190(US10112950, Example 42 | US10556908, Example 42 | ...)
Affinity DataIC50: <50nMpH: 7.5 T: 2°CAssay Description:10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM NaCl, 5 mM DTT) were preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent