BDBM113231 US8633212, 9
SMILES COC1CCC2(Cc3ccc(cc3C22ON(C)C(N)=N2)-c2cccc(OC(F)(F)F)c2)CC1
InChI Key InChIKey=YUXAILNGSXIUQD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 113231
TargetIsoform C of Beta-secretase 1 (BACE-I-457)(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Vitae Pharmaceuticals
US Patent
Affinity DataIC50: 7nMpH: 4.5 T: 2°CAssay Description:Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity. The assay was performed at room temperature in 96-well...More data for this Ligand-Target Pair