BDBM11702 (2S)-Cyanopyrrolidine analogue 18f::1-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-1-oxo-propyl]-4-[4-[1-oxoethylamino]phenylsulfonyl]piperazine::N-[4-({4-[3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)propanoyl]piperazine-1-}sulfonyl)phenyl]acetamide

SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCNCC(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=KEJZQAMISBJAEB-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11702   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11702((2S)-Cyanopyrrolidine analogue 18f | 1-[3-[2-[2-Cy...)
Affinity DataIC50:  1.42E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11702((2S)-Cyanopyrrolidine analogue 18f | 1-[3-[2-[2-Cy...)
Affinity DataIC50: >1.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
National Health Research Institutes

LigandPNGBDBM11702((2S)-Cyanopyrrolidine analogue 18f | 1-[3-[2-[2-Cy...)
Affinity DataIC50:  3.42E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed