BDBM117471 US8653087, III-151

SMILES COCCNc1ncc2ncnc(Nc3cc(ccc3C)C(=O)Nc3cc(OCCN(C)C)cc(c3)C(F)(F)F)c2n1

InChI Key InChIKey=DELWEBOBTTWIEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117471   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117471(US8653087, III-151)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In DepthDetails US Patent