BDBM11907 (2S)-2-(adamantan-1-yl)-2-amino-N-(cyanomethyl)-N-(prop-2-en-1-yl)acetamide::seco-proline-based inhibitor 23

SMILES [H][C@@](N)(C(=O)N(CC=C)CC#N)[C@@]12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=XRNKUHKVLKUHHK-TXTUHRKBSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11907   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM11907((2S)-2-(adamantan-1-yl)-2-amino-N-(cyanomethyl)-N-...)
Affinity DataKi:  37nM ΔG°:  -10.0kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed