BDBM119563 US8680275, 120

SMILES Fc1cccc(c1C(=O)N1CC[C@H]2CN([C@H]2C1)c1nc2cc(Cl)ccc2o1)-n1nccn1

InChI Key InChIKey=MUXDWBWGCFZGSS-UGSOOPFHSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119563   

TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119563(US8680275, 120)
Affinity DataKi:  26nM ΔG°:  -9.61kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119563(US8680275, 120)
Affinity DataKi:  43nM ΔG°:  -9.34kcal/moleT: 2°CAssay Description:Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...More data for this Ligand-Target Pair
In DepthDetails US Patent