BDBM11983 3-(4-chlorophenyl)-1-{4-[(5-ethyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}urea::chemical diversity library compound 8

SMILES CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2)s1

InChI Key InChIKey=CRWJSQKQKOMKTJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11983   

TargetLethal factor(Bacillus anthracis)
Montana State University

LigandPNGBDBM11983(3-(4-chlorophenyl)-1-{4-[(5-ethyl-1,3,4-thiadiazol...)
Affinity DataKi:  900nM ΔG°:  -8.30kcal/mole IC50:  4.80E+3nMpH: 7.2 T: 2°CAssay Description:For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed