BDBM120112 US8697715, 167

SMILES Cc1cc(Nc2nccc(n2)-c2ccn([C@H](CO)c3ccc(Cl)c(F)c3)c(=O)c2)n(C)n1

InChI Key InChIKey=DZJYAXWHKDTIEA-LJQANCHMSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 120112   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120112(US8697715, 167)
Affinity DataIC50:  3.10nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM120112(US8697715, 167)
Affinity DataIC50:  20nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120112(US8697715, 167)
Affinity DataIC50:  13nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120112(US8697715, 167)
Affinity DataIC50:  13nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM120112(US8697715, 167)
Affinity DataIC50:  20nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed