BDBM120135 US8697708, 25

SMILES OC1CN(C1)c1cc(Nc2ncnc3nc(sc23)-c2c(Cl)cccc2Cl)ncn1

InChI Key InChIKey=OZWGBSFIBHULPB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120135   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM120135(US8697708, 25)
Affinity DataKi:  87nM ΔG°:  -9.53kcal/molepH: 7.2 T: 2°CAssay Description:To determine the inhibition constants (Ki) of Examples 1-240, compounds were diluted serially in DMSO and added to 50 μL kinase reactions contai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent