BDBM124942 US8765750, Reference Example 15

SMILES COc1ccc2nc(NC(=O)N3CCN(CC3)C(=O)c3cccc(F)c3)sc2c1

InChI Key InChIKey=LOALUDBNYIAWTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124942   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM124942(US8765750, Reference Example 15)
Affinity DataIC50:  318nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM124942(US8765750, Reference Example 15)
Affinity DataIC50:  318nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In DepthDetails US Patent