BDBM125039 US8772510, 58
SMILES Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1nc(oc1-c1ccccc1)-c1ccccc1
InChI Key InChIKey=ZBFJDHWIKRNEBZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 125039
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 0.700nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair