BDBM12706 4-amino-3-cyano-N-[2-fluoro-4-(2-methanesulfonylphenyl)phenyl]-1-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide::N-arylpyrazole carboxamide 12

SMILES COc1ccc(cc1)-n1nc(C#N)c(N)c1C(=O)Nc1ccc(cc1F)-c1ccccc1S(C)(=O)=O

InChI Key InChIKey=YEICLSYLHFPMDT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12706   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM12706(4-amino-3-cyano-N-[2-fluoro-4-(2-methanesulfonylph...)
Affinity DataKi:  8.40nM ΔG°:  -10.9kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed