BDBM127077 US8785459, 152
SMILES COc1ccc(cc1)-c1ccc2ncnc(Oc3cccc(O)c3)c2c1
InChI Key InChIKey=NMGQBHKJOZFEDA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 127077
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 131nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 198nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair