BDBM127077 US8785459, 152

SMILES COc1ccc(cc1)-c1ccc2ncnc(Oc3cccc(O)c3)c2c1

InChI Key InChIKey=NMGQBHKJOZFEDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 127077   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127077(US8785459, 152)
Affinity DataIC50:  131nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127077(US8785459, 152)
Affinity DataIC50:  2.33E+3nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127077(US8785459, 152)
Affinity DataIC50:  198nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent