BDBM12917 CHEMBL217569::O-propynyl ester derivative 3::Prop-2-ynyl 4-sulfamoylbenzoate::prop-2-yn-1-yl 4-sulfamoylbenzoate

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OCC#C

InChI Key InChIKey=IORJVPBKDUGFOJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 12917   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12917(CHEMBL217569 | O-propynyl ester derivative 3 | Pro...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

LigandPNGBDBM12917(CHEMBL217569 | O-propynyl ester derivative 3 | Pro...)
Affinity DataKi:  45nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM12917(CHEMBL217569 | O-propynyl ester derivative 3 | Pro...)
Affinity DataKi:  83nMAssay Description:Inhibition of human recombinant CA14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Griffith University

LigandPNGBDBM12917(CHEMBL217569 | O-propynyl ester derivative 3 | Pro...)
Affinity DataKi:  104nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

LigandPNGBDBM12917(CHEMBL217569 | O-propynyl ester derivative 3 | Pro...)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.36kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed