BDBM136512 US8865726, 143

SMILES Nc1nnc(o1)-c1ccc(cc1F)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(F)cn1

InChI Key InChIKey=VGTHTBKUXCUYAW-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136512   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM136512(US8865726, 143)
Affinity DataIC50:  6.30nMpH: 7.5 T: 2°CAssay Description:The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...More data for this Ligand-Target Pair
In DepthDetails US Patent