BDBM136692 US8865686, Table 1, Compound 4
SMILES CN(C)C1C2CC3C(=C(O)C2(O)C(=O)C(C(=O)NCNc2cccc(C(O)=O)c2C(O)=O)=C1O)C(=O)c1c(O)cccc1C3(C)O
InChI Key InChIKey=GDFMZNWMFGDDBZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 136692
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services
US Patent
Affinity DataIC50: 4.90E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair