BDBM136712 US10231967, Example 13e::US8865911, 13e::US9918985, Example 13e

SMILES CC#CCOc1cnc(cn1)C(=O)Nc1ccc2OCCC3(N=C(C)C(N)=N3)c2c1

InChI Key InChIKey=LGQYIGQUEVQRCI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136712   

TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM136712(US10231967, Example 13e | US8865911, 13e | US99189...)
Affinity DataIC50:  22nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent