BDBM13792 2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4,6-dioxo-1H,4H,5H,6H-pyrrolo[3,4-d]imidazol-1-yl]methyl}benzonitrile::Xanthine mimetic compound 7

SMILES CN1C(=O)c2nc(N3CCCC(N)C3)n(Cc3ccccc3C#N)c2C1=O

InChI Key InChIKey=WVRGIUWTFUXDGX-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13792   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13792(2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4,6-dioxo-1...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM13792(2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4,6-dioxo-1...)
Affinity DataKi:  2nM ΔG°:  -11.7kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13792(2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4,6-dioxo-1...)
Affinity DataKi: >3.00E+3nM ΔG°: >-7.45kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13792(2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4,6-dioxo-1...)
Affinity DataKi: >3.00E+3nM ΔG°: >-7.45kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed