BDBM138142 US8877967, 3

SMILES CN(N=C(c1ccccc1)c1cccc(c1)C(=O)c1ccccc1)C(N)=S

InChI Key InChIKey=WZWOSKAWLSAHCD-HIXSDJFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 138142   

TargetProcathepsin L(Homo sapiens (Human))
Oxigene

US Patent
LigandPNGBDBM138142(US8877967, 3)
Affinity DataIC50:  10.5nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin B(Homo sapiens (Human))
Oxigene

US Patent
LigandPNGBDBM138142(US8877967, 3)
Affinity DataIC50: >1.00E+4nMpH: 6.0Assay Description:Human liver Cathepsin B (Calbiochem) was pre-incubated with test compound at various concentrations for 5 minutes at 37C. The assay was initiated by ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Oxigene

US Patent
LigandPNGBDBM138142(US8877967, 3)
Affinity DataIC50:  17.4nMpH: 3.5 T: 2°CAssay Description:Recombinant human procathepsin K was obtained from Enzo Life Sciences. Activation of the proenzyme was performed in 32.5 mM sodium acetate pH 3.5, ED...More data for this Ligand-Target Pair
In DepthDetails US Patent