BDBM138148 US8877967, 18
SMILES COc1ccc(cc1)C(=O)c1cccc(c1)C(=NNC(N)=S)c1ccc(O)cc1
InChI Key InChIKey=LRIJLAPJGORVAU-GFMRDNFCSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 138148
Affinity DataIC50: >1.00E+4nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 5.5Assay Description:Human liver Cathepsin L (Sigma) was preincubated with test compounds at various concentrations for 5 minutes at 25C. The assay was initiated by addit...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.0Assay Description:Human liver Cathepsin B (Calbiochem) was pre-incubated with test compound at various concentrations for 5 minutes at 37C. The assay was initiated by ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMpH: 3.5 T: 2°CAssay Description:Recombinant human procathepsin K was obtained from Enzo Life Sciences. Activation of the proenzyme was performed in 32.5 mM sodium acetate pH 3.5, ED...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 6.0Assay Description:Human liver Cathepsin B (Calbiochem) was pre-incubated with test compound at various concentrations for 5 minutes at 37C. The assay was initiated by ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.16E+3nMpH: 3.5 T: 2°CAssay Description:Recombinant human procathepsin K was obtained from Enzo Life Sciences. Activation of the proenzyme was performed in 32.5 mM sodium acetate pH 3.5, ED...More data for this Ligand-Target Pair