BDBM140272 US8907086, Example 8

SMILES Cc1nc(Cn2c3nccc3c(N3CCCC(N)C3)n(Cc3cc(F)ccc3C#N)c2=O)nc2ccccc12

InChI Key InChIKey=XGEBCDBVBVNXEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140272   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM140272(US8907086, Example 8)
Affinity DataIC50:  104nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In DepthDetails US Patent