BDBM140535 US8912221, 8

SMILES COC(=O)c1c(Cl)cccc1-c1ccc([C@@H](C)NC(=O)C2(COC2)NC(=O)CC(F)(F)F)c(F)c1

InChI Key InChIKey=CWJWJHIDQXXJLE-GFCCVEGCSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140535   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM140535(US8912221, 8)
Affinity DataKi:  5.30nMpH: 7.4Assay Description:For binding, Bradykinin-1 receptor antagonist compounds were added in various concentrations in 50 mM Tris pH 7.4, 5 mM MgCl2 together with 6 nM Kall...More data for this Ligand-Target Pair
In DepthDetails US Patent