BDBM141391 US8921319, 15

SMILES OC(=O)[C@@H]1Cc2ccc(NC(=O)CN3CCN(CC3)CC(=O)Nc3ccc(C[C@@H](NS(=O)(=O)Cc4ccccc4)C(=O)N1)cc3)cc2

InChI Key InChIKey=MQTMFZBGEJWSRJ-WDYNHAJCSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 141391   

TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM141391(US8921319, 15)
Affinity DataKi:  0.680nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM141391(US8921319, 15)
Affinity DataKi:  320nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM141391(US8921319, 15)
Affinity DataKi:  8.40E+3nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

US Patent
LigandPNGBDBM141391(US8921319, 15)
Affinity DataKi: >1.00E+4nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent