BDBM141418 US10668051, Compound Example 72::US8921364, 72

SMILES FC(F)(F)c1cc(C2CC2)n(n1)-c1ccc(NC(=O)Cc2cccnc2)cc1

InChI Key InChIKey=HACUWFNZXMLECQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141418   

TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
Rhizen Pharmaceuticals

US Patent
LigandPNGBDBM141418(US10668051, Compound Example 72 | US8921364, 72)
Affinity DataIC50:  48.2nMAssay Description:Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat #T9033) induced endoplasmic calcium release in Jurkat cells, (see Yasur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEF-hand calcium-binding domain-containing protein 4B(Homo sapiens (Human))
Rhizen Pharmaceuticals

US Patent
LigandPNGBDBM141418(US10668051, Compound Example 72 | US8921364, 72)
Affinity DataIC50:  48.2nMT: 2°CAssay Description:Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...More data for this Ligand-Target Pair
In DepthDetails US Patent