BDBM14269 (S)-isothiazolidinone::IZD deriv. 2::N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-{3-methyl-4-[(5S)-1,1,3-trioxo-1,2-thiazolidin-5-yl]phenyl}ethyl]benzenesulfonamide

SMILES Cc1cc(C[C@H](NS(=O)(=O)c2ccccc2)c2nc3ccccc3[nH]2)ccc1[C@@H]1CC(=O)NS1(=O)=O

InChI Key InChIKey=FBFPKPPWVZPZDO-GOTSBHOMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14269   

LigandPNGBDBM14269((S)-isothiazolidinone | IZD deriv. 2 | N-[(1S)-1-(...)
Affinity DataIC50:  35nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM14269((S)-isothiazolidinone | IZD deriv. 2 | N-[(1S)-1-(...)
Affinity DataIC50:  32nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM14269((S)-isothiazolidinone | IZD deriv. 2 | N-[(1S)-1-(...)
Affinity DataIC50:  25nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed