BDBM14322 2-Aminoquinoline 1::2-aminoquinoline::CHEMBL61236::Fragment 19::Quinolin-2-amine::fragment 2 (J. med. chem.,50,1116)

SMILES Nc1ccc2ccccc2n1

InChI Key InChIKey=GCMNJUJAKQGROZ-UHFFFAOYSA-N

Data  5 KI  5 IC50  4 Kd  3 EC50  1 Other

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14322   

TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM14322(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Affinity DataIC50:  2.00E+6nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair