BDBM143375 US9682953, 20.A-11::US9682953, 20.A-12

SMILES FC(F)(F)c1ccc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3cn[nH]c3)c2)nc1

InChI Key InChIKey=VFHRALAVCKZLHR-GDNBJRDFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143375   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM143375(US9682953, 20.A-11 | US9682953, 20.A-12)
Affinity DataIC50:  65nMAssay Description:Inhibition of rat FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM143375(US9682953, 20.A-11 | US9682953, 20.A-12)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human transmembrane domain deficient FFAH expressed in Escherichia coli using AAMCA as substrate incubated for 1 min measured for 50 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed