BDBM14483 2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,3-benzodiazol-3-ium::CA-25

SMILES Nc1[nH]c2ccc(NC(=O)c3cccc(-c4ccccc4)c3O)cc2[nH+]1

InChI Key InChIKey=USQJNQXMUDZZON-UHFFFAOYSA-O

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 14483   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi:  4.10E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi: >7.50E+4nM ΔG°: >-5.57kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi: >7.50E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi:  1.30E+5nM ΔG°:  -5.24kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi:  2.70E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi: >4.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14483(2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,...)
Affinity DataKi: >4.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed