BDBM145261 US8952169, 40::US9771376, Example 41

SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(O[C@H]2C3CC4CC2CC(Cl)(C4)C3)cc1F

InChI Key InChIKey=QNKJCLDQVPZBAW-PZCFEFJCSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145261   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM145261(US8952169, 40 | US9771376, Example 41)
Affinity DataIC50:  13nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM145261(US8952169, 40 | US9771376, Example 41)
Affinity DataIC50:  13nMAssay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent