BDBM145987 US8957068, 22
SMILES CC(C)[C@@H]1COC(=O)N1c1ccnc(N[C@H](C)c2ccccc2)n1
InChI Key InChIKey=CUTPLPKYQGWUBC-HIFRSBDPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 145987
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of human N-terminal 6His-tagged IDH1 R132H mutant expressed in Escherichia coli Rosetta2 (DE3) assessed as effect on intracellular 2-HG le...More data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+4nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair