BDBM146415 US8957068, 543

SMILES CC(C)[C@H]1COC(=O)N1c1ccnc(NC(C)C2CCCO2)n1

InChI Key InChIKey=MLZGJRWEZJAROF-OTTFEQOBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 146415   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM146415(US8957068, 543)
Affinity DataIC50: >2.50E+4nMpH: 7.5 T: 2°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...More data for this Ligand-Target Pair
In DepthDetails US Patent