BDBM147539 US8962608, 17-20
SMILES NC(=O)c1cn(nc1Nc1ccc2C(=O)N(CC(F)(F)F)Cc2c1)[C@H]1CCCC[C@@H]1C#N
InChI Key InChIKey=MJOUHJKBMTXVKJ-PXAZEXFGSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 147539
Affinity DataIC50: 0.790nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair