BDBM150249 US8980932, 6a (DH307)

SMILES Cc1ncc(n1CCNC(=S)Nc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O

InChI Key InChIKey=DFYMFHTYDQHATF-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 150249   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  5.5nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  5.5nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  7.30nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  7.30nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  8nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  8nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  105nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150249(US8980932, 6a (DH307))
Affinity DataKi:  105nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed