BDBM150253 US8980932, 4a (DH296)

SMILES NS(=O)(=O)c1ccc(NC(=O)Cn2ccnc2[N+]([O-])=O)cc1

InChI Key InChIKey=HUFRGRVXHRXCPC-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 150253   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  64nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  64nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-12 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  70nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Maastro-Clinic

US Patent
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  70nMAssay Description:Inhibition of recombinant human catalytic domain of carbonic anhydrase-9 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  330nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  330nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase-1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM150253(US8980932, 4a (DH296))
Affinity DataKi:  3.20E+3nMpH: 7.5Assay Description:The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...More data for this Ligand-Target Pair
In DepthDetails US Patent